Protein degradation : the ubiquitin - proteasome system. Volume 2 / R. John Mayer, Aaron Ciechanover, Martin Rechsteiner, eds.

Contributor(s): Material type: TextTextLanguage: English Publication details: Weinheim : Wiley-VCH, c2005-c2006Description: 3 v. : ill. (some col.) ; 25 cmSubject(s): DDC classification:
  • 612.3 PRO(2) 2006 14
LOC classification:
  • QP551 .P69581755 2005
NLM classification:
  • 2005 G-092
  • QU 55
Online resources:
Incomplete contents:
v. 1. Ubiquitin and the chemistry of life. 1. Brief history of protein degradation and the ubiquitin system / Avram Hershko -- 2. N-terminal ubiquitination: no longer such a rare modification / Aaron Ciechanover -- 3. Evolutionary origin of the activation step during ubiquitin-dependent protein degradation / Hermann Schindelin -- 4. RING fingers and relatives: determinators of protein fate / Kevin L. Lorick ... [et al.] -- 5. Ubiquitin-conjugating enzymes / Michael J. Eddins and Cecile M. Pickart -- 6. The SCF ubiquitin E3 ligase / Leigh Ann Higa and Hui Zhang -- 7. The structural biology of ubiquitin-protein ligases / Ning Zheng and Nikola P. Pavletich -- 8. The deubiquitinating enzymes / Nathaniel S. Russell and Keith D. Wilkinson -- 9. The 26S proteasome / Martin Rechsteiner -- 10. Molecular machines for protein degradation / Matthias Bochtler ... [et al.] -- 11. Proteasome regulator, PA700 (19S regulatory particle) / George N. DeMartino and Cezary Wojcik -- 12. Bioinformatics of ubiquitin domains and their binding partners / Kay Hofmann -- 13. The COP9 signalosome: its possible role in the ubiquitin system --
v. 2. The ubiquitin-proteasome system. 1. Molecular chaperones and the ubiquitin-proteasome system / Cam Patterson and J�org H�ohfeld -- 2. Molecular dissection of autophagy in the yeast Saccharomyces cerevisiae / Yoshinori Ohsumi -- 3. Dissecting intracellular proteolysis using small molecule inhibitors and molecular probes / Huib Ovaa ... [et al.] -- 4. MEKK1: dual function as a protein kinase and a ubiquitin protein ligase / Zhimin Lu and Tony Hunter -- 5. Proteasome activators / Andreas F�orster and Christopher P. Hill -- 6. The proteasome portal and regulation of proteolysis / Monika Bajorek and Michael H. Glickman -- 7. Ubiquity and diversity of the proteosome system / Keiji Tanaka, Hideki Yashiroda, and Shigeo Murata -- 8. Proteasome-interacting proteins / Jean E. O'Donoghue and Colin Gordon -- 9. Structural studies of large, self-compartmentalizing proteases / Beate Rockel, J�urgen Bosch, and Wolfgang Baumeister -- 10. What the archaeal PAN - proteasome complex and bacterial ATP-dependent proteases can teach us about the 26S proteasome / Nadia Benaroudj, David Smith, and Alfred L. Goldberg -- 11. Biochemical functions of ubiquitin and ubiquitin-like protein conjugation / Mark Hochstrasser.
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Includes bibliographical references and index.

v. 1. Ubiquitin and the chemistry of life. 1. Brief history of protein degradation and the ubiquitin system / Avram Hershko -- 2. N-terminal ubiquitination: no longer such a rare modification / Aaron Ciechanover -- 3. Evolutionary origin of the activation step during ubiquitin-dependent protein degradation / Hermann Schindelin -- 4. RING fingers and relatives: determinators of protein fate / Kevin L. Lorick ... [et al.] -- 5. Ubiquitin-conjugating enzymes / Michael J. Eddins and Cecile M. Pickart -- 6. The SCF ubiquitin E3 ligase / Leigh Ann Higa and Hui Zhang -- 7. The structural biology of ubiquitin-protein ligases / Ning Zheng and Nikola P. Pavletich -- 8. The deubiquitinating enzymes / Nathaniel S. Russell and Keith D. Wilkinson -- 9. The 26S proteasome / Martin Rechsteiner -- 10. Molecular machines for protein degradation / Matthias Bochtler ... [et al.] -- 11. Proteasome regulator, PA700 (19S regulatory particle) / George N. DeMartino and Cezary Wojcik -- 12. Bioinformatics of ubiquitin domains and their binding partners / Kay Hofmann -- 13. The COP9 signalosome: its possible role in the ubiquitin system --

v. 2. The ubiquitin-proteasome system. 1. Molecular chaperones and the ubiquitin-proteasome system / Cam Patterson and J�org H�ohfeld -- 2. Molecular dissection of autophagy in the yeast Saccharomyces cerevisiae / Yoshinori Ohsumi -- 3. Dissecting intracellular proteolysis using small molecule inhibitors and molecular probes / Huib Ovaa ... [et al.] -- 4. MEKK1: dual function as a protein kinase and a ubiquitin protein ligase / Zhimin Lu and Tony Hunter -- 5. Proteasome activators / Andreas F�orster and Christopher P. Hill -- 6. The proteasome portal and regulation of proteolysis / Monika Bajorek and Michael H. Glickman -- 7. Ubiquity and diversity of the proteosome system / Keiji Tanaka, Hideki Yashiroda, and Shigeo Murata -- 8. Proteasome-interacting proteins / Jean E. O'Donoghue and Colin Gordon -- 9. Structural studies of large, self-compartmentalizing proteases / Beate Rockel, J�urgen Bosch, and Wolfgang Baumeister -- 10. What the archaeal PAN - proteasome complex and bacterial ATP-dependent proteases can teach us about the 26S proteasome / Nadia Benaroudj, David Smith, and Alfred L. Goldberg -- 11. Biochemical functions of ubiquitin and ubiquitin-like protein conjugation / Mark Hochstrasser.

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