000			03034nam a2200361 a 4500
001			vtls000129206
003			VRT
005			20240802185152.0
008			141217 xxu 000 0 eng d
020			_a9781466577435
039		9	_a201504270317 _bVLOAD _c201502081557 _dVLOAD _c201501131048 _dyenh _c201501091603 _dbactt _y201412170957 _zthupt
040			_aVNU
041	1		_aeng
044			_aUS
082	1		_a616.994061 _bDNA 2013
090			_a616.99 _bDNA 2013
245	0	0	_aDNA repair and cancer : from bench to clinic / editors, Srinivasan Madhusudan, David M. Wilson III.
260			_aBoca Raton : Taylor & Francis, 2013.
300			_a700 p.
505			_aOverview of DNA repair pathways / Deborah L. Croteau and Vilhelm A. Bohr -- Longevity assurance by genome maintenance / Paul Hasty, Yousin Suh and Jan Vijg -- Genetic instability of cancer : biological predictions and clinical implications / Robert A. Beckman -- Radiation induced DNA damage, repair, and therapeutics / Lynn Harrison -- Chemotherapeutic alkylating agents in cancer treatment / Tracey D. Bradshaw -- O6-methylguanine-DNA methyltransferase (MGMT) in cancer protection and therapy / Bernd Kaina and Markus Christmann -- DNA mismatch repair : it's role in human carcinogenesis and as a predictive and/or prognostic biomarker for cancer therapy / Timothy J. Kinsella -- DNA base excision repair therapeutics : summary of targets with a focus on APE1 / Melissa L. Fishel, Carlo Vascotto and Mark R. Kelley -- Nucleotide excision repair : DNA repair capacity variability and cancer susceptibility / Li-E Wang and Qingyi Wei -- Fanconi anemia, interstrand cross-link repair, and cancer / Taraswi Banerjee, Sanjay Kumar Bharti and Robert M. Brosh, Jr -- Functions of translesion DNA polymerases : implications for cancer risk and opportunities as therapeutic targets / Kinrin Yamanaka and R. Stephen Lloyd -- P53 in DNA damage, repair and cancer therapeutics / Aditi Gurkar, Kiki Chu and Sam W. Lee -- ATM/ATR cell cycle checkpoints : mechanisms and manipulation in cancer therapy / Marie Fernet, Sara Chiker and Janet Hall -- The BRCA1-BRCA2 pathway of homologous recombination and the opportunity for synthetic lethal approaches to cancer therapy / Laura J. Eccles ... [et al.] -- PARP and PARP inhibitor therapeutics / Nicola J. Curtin -- Tumor genetics and personalized medicine / Mary Ellen Urick and Daphne W. Bell -- The tumor microenvironment and DNA repair : implications for cancer progression and treatment / Norman Chan, Shaqil Kassam and Robert G. Bristow -- Early phase clinical trials using DNA repair inhibitors : lessons learnt / Miranda Payne and Mark Middleton.
650		0	_aNeoplasms--genetics.
650		0	_aDNA Damage--drug effects.
650		0	_aDNA Damage--physiology.
650		0	_aDNA Repair--drug effects.
653			_aBệnh ung thư
653			_aĐiều trị
700	1		_aMadhusudan, Srinivasan.
700	1		_aWilson, David M., 1967-
900			_aTrue
925			_aG
926			_a0
942			_c1
999			_c360652 _d360652